WP1. Project management and coordination.
WP leader: Maastricht (van den Hove, Rutten, Senden); WP co-leader: Exeter (Lunnon, Mill)
WP2. DNA (hydroxy)methylome screening (Objectives I-III).
WP leader: Exeter (Lunnon, Mill); WP co-leader: Maastricht (Van den Hove, Rutten); Other partner(s): Wuerzburg (Haaf, Lesch), Luxembourg (Del Sol, Glaab, Balling); Companies (SMEs): GenomeScan/ServiceXS
WP3. Limiting Dilution Bisulfite Sequencing on DNA collected via Laser Capture Microdissection (Objective I).
WP leader: Wuerzburg (Haaf, Lesch); WP co-leader: New York (Ginsberg); Other partner(s): Sun City (Mastroeni, Coleman), Maastricht (Jacobs, Van den Hove, Rutten), Exeter (Lunnon, Mill), Luxembourg (Del Sol Mesa, Glaab, Balling).
WP4. Epigenetic screening of the blood in longitudinal aging cohorts (Objective III).
WP leader: Bonn (Ramirez, Wagner); WP co-leader: Maastricht (Aalten, Verhey, Ramakers, Van den Hove, Rutten); Other partner(s): Wuerzburg (Haaf, Lesch), Luxembourg (Del Sol Mesa, Glaab, Balling).
WP5. Novel advanced iPSC model system on AD (Objective IV).
WP leader: Barcelona (Esteller, Delgado); WP co-leader: Maastricht (Van den Hove, Rutten, Kenis); Other partner(s): Würzburg (Haaf, Lesch), Luxembourg (Del Sol, Glaab, Balling).
WP6. Bioinformatics (Objectives I-IV).
WP leader: Luxembourg (Del Sol, Glaab, Balling); WP co-leader: Exeter (Lunnon, Mill), Maastricht (Kleinjans); Other partner(s): n.a.
WP7. Training.
WP leader: Maastricht (Senden, Van den Hove, Rutten, Aalten); WP co-leader: Exeter (Lunnon, Mill); Other partner(s): Wuerzburg (Haaf, Lesch, Ortega), Bonn (Ramirez, Wagner), Luxembourg (Del Sol, Glaab, Balling), Barcelona (Esteller, Delgado).